Publications

13. Liu, H.; Zeng, T.; He, C.; Rawal, V.H.; Zhou, H*.; Dickinson, B.C*. (2022) Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA. ACS Chemical Biology Article ASAP.

DOI: 10.1021/acschembio.2c00178

12. Rangadurai, A.; Shi, H.; Xu, Y.; Liu, B.; Assi, H. A.; Boom, J.D.; Zhou, H.;  Kimsey, I. J.; Al-Hashimi, H.M. (2022) Measuring thermodynamic preferences to form non-native conformations in nucleic acids using melting experiments reveals a rich sequence-specific DNA conformational landscape. BioRxiv.

11. Shafik, A.M., Zhou H., Lim J., Dickinson, B.C., Jin P. (2021) Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer’s disease. Hum. Mol. Genet. ddab357.

10. Zhou, H.; Rauch, S.; Dai, Q.; Cui, X.; Zhang, Z.; Nachtergaele, S.; Sepich, C.; He, C.; Dickinson, B.C. (2019) Evolution of A Reverse Transcriptase to Map N1-Methyladenosine in Human mRNA. Nature Methods. 16, 1281-1288.

9. Rauch, S.; He E.; Scienc M.; Zhou, H.; Zhang, Z.; Dickinson, B.C. (2019) Programmable RNA-Guided RNA Effector Proteins Built from Human Parts. Cell. 178, 8-9.

8. Zhou, H.; Sathyamoorthy, B.; Stelling, A.; Xu, Y.; Xue, Y.;  Pigli, Y. Z.; Case, D.; Rice, P. A.; Al-Hashimi, H. M. (2019) Resolving crystallographic ambiguity in Watson-Crick versus Hoogsteen base-pairing in a DNA-protein complex using NMR and site-specifically 13C/15N labeled DNA. Biochemistry, 58, 1963-1974.

7. Rangadurai, A.; Zhou, H.; Merriman, D.; Meiser, N.; Liu, B.; Shi, H.; Szymanski, E.; Al-Hashimi, H.M. (2018) Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? Nucleic Acids Res., 46, 11099-11114.

6. Sathyamoorthy, B.; Shi, H.; Zhou, H.; Xue, Y; Rangadurai A.; Merriman D. K.; Al-Hashimi, H. M. (2017) Insights into Watson-Crick/Hoogsteen Breathing Dynamics and Damage Repair from the Solution Structure and Dynamic Ensemble of DNA Duplexes containing m1A. Nucleic Acids Res., 45, 5586-5601.

5. Stelling, A.; Xu, Y.; Zhou, H.; Choi, S.; Clay, M.; Merriman, D.; Al-Hashimi, H. M. (2017) Robust IR Based Detection of Stable and Fractionally Populated G‐C+ and A‐T Hoogsteen Base Pairs in Duplex DNA. FEBS Letters, 591, 1770-1784.

4. Zhou, H.; Kimsey, I. J.; Nikolova, E. N.; Sathyamoorthy, B.;Grazioli, G.; McSally, J.;Bai, T.; Wunderlich, C. H.; Kreutz,C.; Andricioaei, I.;Al-Hashimi, H. M. (2016) m1A and m1G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs. Nat. Struct. Mol. Biol., 23, 803-810.

3. Zhou, H.; Hintze B.J.; Kimsey, I. J.; Sathyamoorthy, B.; Yang S.; Richardson, J.S.; Al-Hashimi, H. M. (2015) New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey. Nucleic Acids Res., 43, 3420-3433.

2. Nikolova, E.N.; Zhou, H.; Gottardo F.L.; Alvey, H. S.; Kimsey, I. J.; Al-Hashimi, H. M. (2013) A Historical Account of Hoogsteen Base-Pairs in Duplex DNA. Biopolymers,99, 955-968.

1. Goh, G.B.; Hulbert B.S.; Zhou, H.; Brooks. C.L. 3rd. (2014) Constant pH molecular dynamics of proteins in explicit solvent with proton tautomerism. Proteins, 82, 1319-1331.