Glenn R. Gaudette

John W. Kozarich ’71 Chair of the Department of Engineering

Professor

Photo of Glenn R. Gaudette

Glenn R. Gaudette

Contact

245 Beacon Street, Room 511

Telephone: 617-552-2049

Email: glenn.gaudette@bc.edu

Profile

Glenn Gaudette, a biomedical engineer who has pioneered the use of plants as scaffolding for heart regeneration, has been named the inaugural chair of Boston College’s new Engineering Department, which will integrate BC’s liberal arts focus with a human-centered engineering curriculum to prepare students to find solutions that address critical human needs.

His research, supported by the National Institutes of Health and the National Science Foundation, aims to develop a treatment for the millions of Americans suffering from myocardial infarction and other cardiovascular diseases. His work is also focused on the cultivation of protein products as sustainable food sources with reduced environmental impact.

Selected Publications

  1. Gershlak JR, Hernandez S, Fontana G, Perreault LR, Hansen KJ, Larson SA, Binder BY, Dolivo DM, Yang T, Dominko T, Rolle MW, Weathers PJ, Medina-Bolivar F, Cramer CL, Murphy WL, Gaudette GR. Crossing kingdoms: Using decellularized plants as perfusable tissue engineering scaffolds. Biomaterials. 2017 May;125:13-22.
  2. Fontana G, Gershlak J, Adamski M, Lee JS, Matsumoto S, Le HD, Binder B, Wirth J, Gaudette G, Murphy WL. Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture. Advanced Healthcare Materials. 2017, 6(8).
  3. Jank BJ, Goverman J, Guyette JP, Charest JM, Randolph MA, Gaudette GR, Gershlak JR, Purschke M, Javorsky E, Nazarian RM, Leonard DA, Cetrulo CL, Austen WG Jr, Ott HC. Creation of a Bioengineered Skin Flap Scaffold with a Perfusable Vascular Pedicle. Tissue Engineering Part A. 2017, 23(13-14):696-707.
  4. Hansen KJ, Favreau JT, Gershlak JR, Laflamme MA, Albrecht DR, Gaudette GR. Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Tissue Engineering Part C: Methods. 2017, 23(8): 445-454.
  5. Hansen KJ, Laflamme MA, Gaudette GR. Development of a Contractile Cardiac Fiber from Pluripotent Stem Cell Derived Cardiomyocytes. Frontiers in Cardiovascular Medicine. 2018 5, 52.
  6. Adamski M, Fontana G, Gershlak JR, Gaudette GR, Le HD, Murphy WL. Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications. Journal of Visual Experiments. (135), e57586, 2018.
  7. DiBiasio D, Boudreau K, Dodson L, Quinn P, Bergendahl J, Sullivan JM, Gaudette GR, Abel C, Robinson LA, Wodin-Schwartz S. Many Hands on the Elephant: How a Transdisciplinary Team Assesses an Integrative Course. 2018 ASEE Annual Conference & Exposition, 2018, https://peer.asee.org/30787.
  8. Hutcheson JD, Goergen CJ, Schoen FJ, Aikawa M, Zilla P, Aikawa E, Gaudette GR. After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective from the International Society for Applied Cardiovascular Biology. Frontiers in Cardiovascular Medicine. 2019, 6 (e-pub).
  9. Carlson C, Polizzotto L, Gaudette GR. The “NABC's” of Value Propositions. IEEE Engineering Management Review. 2019, 47(3), 15-20.
  10. Moser PT, Gerli M, Diercks GR, Evangelista-Leite D, Charest JM, Gershlak JR, Ren X, Gilpin SE, Jank BJ, Gaudette GR, Hartnick CJ, Ott HC. Creation of Laryngeal Grafts from Primary Human Cells and Decellularized Laryngeal Scaffolds. Tissue Engineering Part A. 2020, 26:543-555.
  11. Robbins ER, Pins GD, Laflamme MA, Gaudette GR. Creation of a contractile biomaterial from a decellularized spinach leaf without ECM protein coating: An in vitro study. Journal of Biomedical Materials Research Part A. 2020, 108 (10), 2123-2132.
  12. Jones JD, Rebello AS, Gaudette GR. Decellularized spinach: An edible scaffold for lab-grown meat. Food Bioscience 2021, 41, 100986.

Patents

  • Systems and methods for mapping and ablation in the bladder (with M Boden, S Nagale, Y Mendelson, D Cavallaro*, T Richardson*, T Hickey*, R Shuraim*, D Goksun*)
    US Patent # 11,083,516; Issued August 10, 2021; * = undergraduate students
  • Decellularization of Plant Cell Culture Materials for Tissue Engineering and Drug Delivery (with J Coburn, N Phan)
    US Patent # 11,110,203; Issued: September 7, 2021
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